| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
LLGL2 / HGL |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 1:500-1000 |
| Intented use: |
This LLGL2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
3993 |
| Uniprot #: |
Q6P1M3 |
| Purity: |
SAS precipitation followed by dialysis in PBS |
| Description: |
In fly, In human, LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila, and cell migration, epithelial cell polarity, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC), this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells, The lethal (2) giant larvae protein of Drosophila / Human giant larvae homolog plays a role in asymmetric cell division |
| Immunogen: |
A portion of amino acids 165-199 from the human protein was used as the immunogen for the LLGL2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the LLGL2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
LLGL2 / HGL |
| Short name: |
LLGL2 Antibody / HGL |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
lethal giant larvae homolog 2 (Drosophila) (Antibody to) / HGL |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, Cytoplasm, HGL and LGL2, LLGL2 and IDBG-68503 and ENSG00000073350 and 3993, Llgl2 and IDBG-214360 and ENSMUSG00000020782 and 217325, PDZ domain binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006887 and exocytosis and biological process this GO :0007049 and cell cycle and biological process this GO :0030165 and PDZ domain binding and molecular function this GO :0032878 and regulation of establishment or maintenance of cell polarity and biological process this GO :0051301 and cell division and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0030165 : PDZ domain binding, this GO :0030165 : PDZ domain binding, 52154 and IDBG-643198 and ENSBTAG00000020067 and 539545, lethal giant larvae homolog 2 (Drosophila) |
| Identity: |
6629 |
| Gene: |
LLGL2 |
More about : LLGL2 |
| Long gene name: |
LLGL2, scribble cell polarity complex component |
| Synonyms gene name: |
lethal giant larvae homolog 2 (Drosophila) lethal giant larvae homolog 2, scribble cell polarity complex component |
| Synonyms: |
HGL Hugl-2 |
| Locus: |
17q25, 1 |
| Discovery year: |
1997-01-28 |
| GenBank acession: |
X87342 |
| Entrez gene record: |
3993 |
| Pubmed identfication: |
22580609 |
| RefSeq identity: |
NM_004524 |
| Classification: |
Scribble complex WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000179685 |