| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AURKC |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the AURKC antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This AURKC antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9UQB9 |
| Purity: |
Purified |
| Description: |
Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis, Aurora-C expression is maximum at M phase, Elevated expression levels are seen only in a subset of cancer cells such as HepG2, Expression is limited to testis in normal cells, HuH7 and HeLa cells, The Aurora kinases, This protein is localized to centrosome from anaphase to cytokinesis, associate with microtubules during chromosome movement and segregation, members of the Ser/Thr protein kinase family, Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases |
| Immunogen: |
A portion of the C-terminal region of the human protein was used as immunogen for this AURKC antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AURKC antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AURKC |
| Short name: |
AURKC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
aurora kinase C (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AIE2 and AIK3 and ARK3 and AurC and aurora-C and SPGF5 and STK13, AURKC and IDBG-71872 and ENSG00000105146 and 6795, Aurkc and IDBG-141309 and ENSMUSG00000070837 and 20871, centromeric region and cellular component this GO :0000793 and condensed chromosome and cellular component this GO :0000910 and cytokinesis and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005819 and spindle and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007126 and meiotic nuclear division and biological process this GO :0008608 and attachment of spindle microtubules to kinetochore and biological process this GO :0016570 and histone modification and biological process this GO :0016772 and transferase activity, nuclei, this GO :0000775 and chromosome, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004712 : protein serine/threonine/tyrosine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004712 : protein serine/threonine/tyrosine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0030496 and midbody and cellular component this GO :0032133 and chromosome passenger complex and cellular component this GO :0032467 and positive regulation of cytokinesis and biological process this GO :0051233 and spindle midzone and cellular component this GO :0051256 and spindle midzone assembly involved in mitosis and biological process, aurora kinase C |
| Identity: |
11391 |
| Gene: |
AURKC |
More about : AURKC |
| Long gene name: |
aurora kinase C |
| Synonyms gene: |
STK13 |
| Synonyms gene name: |
serine/threonine kinase 13 (aurora/IPL1-like) |
| Synonyms: |
AurC ARK3 |
| Locus: |
19q13, 43 |
| Discovery year: |
1998-05-13 |
| Entrez gene record: |
6795 |
| Pubmed identfication: |
9799611 |
| RefSeq identity: |
NM_003160 |
| Havana BLAST/BLAT: |
OTTHUMG00000183106 |