| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
p16INK4A |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:2000 |
| Notes: |
Titration of the p16INK4A antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This p16INK4A antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P42771 |
| Purity: |
Antigen affinity |
| Description: |
This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein, Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6 |
| Immunogen: |
This p16INK4A antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 145-176 amino acids from human p16-INK4A |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the p16INK4A antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
p16INK4A |
| Short name: |
p16INK4A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p16INK4A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1787 |
| Gene: |
CDKN2A |
More about : CDKN2A |
| Long gene name: |
cyclin dependent kinase inhibitor 2A |
| Synonyms gene: |
CDKN2 MLM |
| Synonyms gene name: |
cyclin-dependent kinase inhibitor 2A (melanoma, inhibits CDK4) , p16 |
| Synonyms: |
CDK4I p16 INK4a MTS1 CMM2 ARF p19 p14 INK4 p16INK4a p19Arf p14ARF |
| Locus: |
9p21, 3 |
| Discovery year: |
1994-05-19 |
| GenBank acession: |
L27211 |
| Entrez gene record: |
1029 |
| Pubmed identfication: |
8152487 7606716 |
| RefSeq identity: |
NM_000077 |
| Havana BLAST/BLAT: |
OTTHUMG00000019686 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database LRG_11 |