| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CCR1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000-2000 |
| Notes: |
Titration of the CCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CCR1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P32246 |
| Purity: |
Antigen affinity |
| Description: |
Binds to MIP-1-alpha, MIP-1-delta, RANTES, Responsible for affecting stem cell proliferation, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level, Receptor for a C-C type chemokine |
| Immunogen: |
This CCR1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 13-44 amino acids from the N-terminal region of human CCR1 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CCR1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CCR1 |
| Short name: |
CCR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-C motif) receptor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CCR1 and IDBG-30085 and ENSG00000163823 and 1230, CD191 and CKR-1 and CKR1 and CMKBR1 and HM145 and MIP1aR and SCYAR1, Cell surfaces, chemokine (C-C motif) ligand 5 binding, coupled to cyclic nucleotide second messenger and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008152 and metabolic process and biological process this GO :0009611 and response to wounding and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0010629 and negative regulation of gene expression and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019957 and C-C chemokine binding and molecular function this GO :0030502 and negative regulation of bone mineralization and biological process this GO :0035717 and chemokine (C-C motif) ligand 7 binding and molecular function this GO :0045672 and positive regulation of osteoclast differentiation and biological process this GO :0051928 and positive regulation of calcium ion transport and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071791 and chemokine (C-C motif) ligand 5 binding and molecular function this GO :0090026 and positive regulation of monocyte chemotaxis and biological process, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0004435 and phosphatidylinositol phospholipase C activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006816 and calcium ion transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006887 and exocytosis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007187 and G-protein coupled receptor signaling pathway, this GO :0004435 : phosphatidylinositol phospholipase C activity, this GO :0004435 : phosphatidylinositol phospholipase C activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0005515 : protein binding and also this GO :0016493 : C-C chemokine receptor activity and also this GO :0019957 : C-C chemokine binding and also this GO :0035717 : chemokine (C-C motif) ligand 7 binding and also this GO :0071791 : chemokine (C-C motif) ligand 5 binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0005515 : protein binding, this GO :0016493 : C-C chemokine receptor activity, this GO :0019957 : C-C chemokine binding, this GO :0035717 : chemokine (C-C motif) ligand 7 binding, this GO :0071791 : chemokine (C-C motif) ligand 5 binding, chemokine (C-C motif) receptor 1 |
| Identity: |
1602 |
| Gene: |
CCR1 |
More about : CCR1 |
| Long gene name: |
C-C motif chemokine receptor 1 |
| Synonyms gene: |
SCYAR1 CMKBR1 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 1 |
| Synonyms: |
CKR-1 MIP1aR CD191 |
| Locus: |
3p21, 31 |
| Discovery year: |
1993-10-14 |
| Entrez gene record: |
1230 |
| Pubmed identfication: |
7679328 |
| RefSeq identity: |
NM_001295 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133451 |