| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CCR2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the CCR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CCR2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P41597 |
| Purity: |
Antigen affinity |
| Description: |
Alternative coreceptor with CD4 for HIV-1 infection, CCL7 and CCL13 chemokines, Transduces a signal by increasing intracellular calcium ion levels, Receptor for the CCL2 |
| Immunogen: |
This CCR2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 336-369 amino acids from the C-terminal region of human CCR2 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CCR2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CCR2 |
| Short name: |
CCR2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-C motif) receptor 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CCR2 and IDBG-30182 and ENSG00000121807 and 729230, Plasma membranes, alpha-beta T cell extravasation and biological process this GO :2000464 and positive regulation of astrocyte chemotaxis and biological process this GO :2000473 and positive regulation of hematopoietic stem cell migration and biological process, protein homodimerization activity, this GO :0001974 and blood vessel remodeling and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002827 and positive regulation of T-helper 1 type immune response and biological process this GO :0002829 and negative regulation of type 2 immune response and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007194 and negative regulation of adenylate cyclase activity and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009611 and response to wounding and biological process this GO :0010574 and regulation of vascular endothelial growth factor production and biological process this GO :0010820 and positive regulation of T cell chemotaxis and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019725 and cellular homeostasis and biological process this GO :0030425 and dendrite and cellular component this GO :0031727 and CCR2 chemokine receptor binding and molecular function this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032743 and positive regulation of interleukin-2 production and biological process this GO :0035705 and T-helper 17 cell chemotaxis and biological process this GO :0042535 and positive regulation of tumor necrosis factor biosynthetic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043204 and perikaryon and cellular component this GO :0043310 and negative regulation of eosinophil degranulation and biological process this GO :0045087 and innate immune response and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0090026 and positive regulation of monocyte chemotaxis and biological process this GO :0090265 and positive regulation of immune complex clearance by monocytes and macrophages and biological process this GO :2000439 and positive regulation of monocyte extravasation and biological process this GO :2000451 and positive regulation of CD8-positive, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0016493 : C-C chemokine receptor activity and also this GO :0031727 : CCR2 chemokine receptor binding and also this GO :0042803 : protein homodimerization activity, this GO :0004950 : chemokine receptor activity, this GO :0016493 : C-C chemokine receptor activity, this GO :0031727 : CCR2 chemokine receptor binding, this GO :0042803 : protein homodimerization activity, 63814 and IDBG-647810 and ENSBTAG00000013586 and 539002, chemokine (C-C motif) receptor 2 |
| Identity: |
1603 |
| Gene: |
CCR2 |
More about : CCR2 |
| Long gene name: |
C-C motif chemokine receptor 2 |
| Synonyms gene: |
CMKBR2 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 2 |
| Synonyms: |
CC-CKR-2 CKR2 MCP-1-R CD192 FLJ78302 |
| Locus: |
3p21, 31 |
| Discovery year: |
1995-05-30 |
| Entrez gene record: |
729230 |
| Pubmed identfication: |
8146186 |
| RefSeq identity: |
NM_000647 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000156466 |