| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ROS1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the ROS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ROS1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P08922 |
| Purity: |
Antigen affinity |
| Description: |
IRS1 and PLCG2, MAPK1, MAPK3, May activate other downstream signaling proteins including AKT1, May activate several downstream signaling pathways related to cell differentiation, May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth, Mediates the phosphorylation and the activation of VAV3, Mediates the phosphorylation of PTPN11, a guanine nucleotide exchange factor regulating cell morphology, an activator of this pathway, growth and survival including the PI3 kinase-mTOR signaling pathway, proliferation, Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium |
| Immunogen: |
This ROS1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1744-1777 amino acids from the C-terminal region of human ROS1 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ROS1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ROS1 |
| Short name: |
ROS1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ROS1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10261 |
| Gene: |
ROS1 |
More about : ROS1 |
| Long gene name: |
ROS proto-oncogene 1, receptor tyrosine kinase |
| Synonyms gene name: |
receptor tyrosine kinase , v-ros avian UR2 sarcoma virus oncogene homolog 1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) c-ros oncogene 1 |
| Synonyms: |
MCF3 ROS c-ros-1 |
| Locus: |
6q22, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M13599 |
| Entrez gene record: |
6098 |
| Pubmed identfication: |
1611909 |
| Classification: |
Fibronectin type III domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000016188 |
| Locus Specific Databases: |
LRG_997 |