| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FIS1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the FIS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This FIS1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y3D6 |
| Purity: |
Antigen affinity |
| Description: |
Also mediates peroxisomal fission, Can induce cytochrome c release from the mitochondrion to the cytosol, Plays a minor role in the recruitment and association of the fission mediator dynamin- related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission, ultimately leading to apoptosis, Involved in the fragmentation of the mitochondrial network and its perinuclear clustering |
| Immunogen: |
This FIS1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 6-40 amino acids from the N-terminal region of human FIS1 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the FIS1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FIS1 |
| Short name: |
FIS1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
cerevisiae) (Antibody to), fission 1 (mitochondrial outer membrane) homolog (S |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
FIS1 and IDBG-234267 and ENSG00000214253 and 51024, FIS1 and IDBG-640356 and ENSBTAG00000007900 and 615565, Fis1 and IDBG-204681 and ENSMUSG00000019054 and 66437, Plasma membranes, cerevisiae), protein binding, this GO :0000266 and mitochondrial fission and biological process this GO :0000422 and mitochondrion degradation and biological process this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005779 and integral component of peroxisomal membrane and cellular component this GO :0006626 and protein targeting to mitochondrion and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0008053 and mitochondrial fusion and biological process this GO :0010821 and regulation of mitochondrion organization and biological process this GO :0016020 and membrane and cellular component this GO :0016559 and peroxisome fission and biological process this GO :0031307 and integral component of mitochondrial outer membrane and cellular component this GO :0032471 and negative regulation of endoplasmic reticulum calcium ion concentration and biological process this GO :0035584 and calcium-mediated signaling using intracellular calcium source and biological process this GO :0043234 and protein complex and cellular component this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043653 and mitochondrial fragmentation involved in apoptotic process and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051561 and positive regulation of mitochondrial calcium ion concentration and biological process this GO :0070584 and mitochondrion morphogenesis and biological process this GO :0090141 and positive regulation of mitochondrial fission and biological process this GO :0090314 and positive regulation of protein targeting to membrane and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, fission 1 (mitochondrial outer membrane) homolog (S |
| Identity: |
21689 |
| Gene: |
FIS1 |
More about : FIS1 |
| Long gene name: |
fission, mitochondrial 1 |
| Synonyms gene: |
TTC11 |
| Synonyms gene name: |
cerevisiae) , tetratricopeptide repeat domain 11 fission 1 (mitochondrial outer membrane) homolog (yeast) fission 1 (mitochondrial outer membrane) homolog (S |
| Synonyms: |
CGI-135 H_NH0132A01, 6 Fis1 |
| Synonyms name: |
CGI-135 protein mitochondrial fission molecule |
| Locus: |
7q22, 1 |
| Discovery year: |
2003-07-09 |
| GenBank acession: |
AF151893 |
| Entrez gene record: |
51024 |
| Pubmed identfication: |
14996942 16010987 |
| RefSeq identity: |
NM_016068 |
| Classification: |
Tetratricopeptide repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000157106 |