Cyclin D2 Antibody (CCND2)

Catalog number:	F52197-0.08ML Buy Now
Price:	265 €
Supplier:	MBS Polyclonals
Product name:	Cyclin D2 Antibody (CCND2)
Quantity:	0.06 ml
Other quantities:	0.08 ml 199€ 0.4 ml 406€
Related search:	ccnd antibody antibodies gene deg term

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Category:	Antibody
Concentration:	pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form:	Antigen affinity purified
Conjugation:	Unconjugated
Clone:	Polyclonal antibody
Recognised antigen:	Cyclin D2 (CCND2)
Host animal:	Rabbit (Oryctolagus cuniculus)
Clonality:	Polyclonal (rabbit origin)
Species reactivity:	Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus)
Tested applications:	ELISA, WB
Recommended dilutions:	Western blot: 1:1000
Notes:	Titration of the CCND2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use:	This CCND2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #:	P30280
Purity:	Antigen affinity
Description:	Also substrate for SMAD3, Component of the ternary complex, Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals, Hypophosphorylates RB1 in early G(1) phase, Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase, cyclin D2/CDK4/CDKN1B, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity), Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition
Immunogen:	A portion of amino acids 258-285 from the mouse protein was used as the immunogen for this CCND2 antibody
Storage:	Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CCND2 antibody and store frozen at -20 deg
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target:	Cyclin D2 (CCND2)
Short name:	Cyclin D2 Antibody (CCND2)
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	Cyclin D2 (Antibody to) (CCND2)
Alternative technique:	antibodies
Identity:	1583
Gene:	CCND2 | More about : CCND2
Long gene name:	cyclin D2
Synonyms name:	G1/S-specific cyclin D2
Locus:	12p13, 32
Discovery year:	1991-12-10
GenBank acession:	AF518005
Entrez gene record:	894
Pubmed identfication:	1386335
RefSeq identity:	NM_001759
Classification:	Cyclins
Havana BLAST/BLAT:	OTTHUMG00000168123

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