| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
BCL11A |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the BCL11A antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This BCL11A antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9H165 |
| Purity: |
Antigen affinity |
| Description: |
The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6, BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein |
| Immunogen: |
A portion of amino acids 806-835 from the human protein was used as the immunogen for this BCL11A antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the BCL11A antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
BCL11A |
| Short name: |
BCL11A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
B-cellular CLL/lymphoma 11A (zinc finger protein) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BCL11A and IDBG-52891 and ENSG00000119866 and 53335, BCL11A and IDBG-634272 and ENSBTAG00000016534 and 538680, Bcl11a and IDBG-155906 and ENSMUSG00000000861 and 14025, DNA-templated and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0010977 and negative regulation of neuron projection development and biological process this GO :0016604 and nuclear body and cellular component this GO :0016925 and protein sumoylation and biological process this GO :0030183 and B cell differentiation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0030517 and negative regulation of axon extension and biological process this GO :0032463 and negative regulation of protein homooli this GO merization and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048671 and negative regulation of collateral sprouting and biological process this GO :0048672 and positive regulation of collateral sprouting and biological process this GO :0050773 and regulation of dendrite development and biological process this GO :2000171 and negative regulation of dendrite development and biological process, nuclei, protein heterodimerization activity, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003714 : transcription corepressor activity and also this GO :0005515 : protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046872 : metal ion binding and also this GO :0046982 : protein heterodimerization activity, this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003714 : transcription corepressor activity, this GO :0005515 : protein binding, this GO :0042803 : protein homodimerization activity, this GO :0046872 : metal ion binding, this GO :0046982 : protein heterodimerization activity, B-cell CLL/lymphoma 11A (zinc finger protein) |
| Identity: |
13221 |
| Gene: |
BCL11A |
More about : BCL11A |
| Long gene name: |
B-cell CLL/lymphoma 11A |
| Synonyms gene: |
EVI9 |
| Synonyms gene name: |
ecotropic viral integration site 9 B-cell CLL/lymphoma 11A (zinc finger protein) |
| Synonyms: |
BCL11A-XL BCL11A-L BCL11A-S CTIP1 HBFQTL5 ZNF856 |
| Locus: |
2p16, 1 |
| Discovery year: |
2001-02-28 |
| GenBank acession: |
AJ404611 |
| Entrez gene record: |
53335 |
| Pubmed identfication: |
11719382 18245381 |
| RefSeq identity: |
NM_022893 |
| Classification: |
Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000129420 |
| Locus Specific Databases: |
The Globin Gene Server |