| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CEBPA |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, FACS |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the CEBPA antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CEBPA antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P49715 |
| Purity: |
Antigen affinity |
| Description: |
Also, It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma, This protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis, the protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells, CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers |
| Immunogen: |
A portion of amino acids 304-330 from the human protein was used as the immunogen for this CEBPA antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CEBPA antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CEBPA |
| Short name: |
CEBPA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
a (Antibody to), CCAAT/enhancer binding protein (C/EBP) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C/EBP-alpha and CEBP, CEBPA and IDBG-409028 and ENSG00000245848 and 1050, Cebpa and IDBG-173713 and ENSMUSG00000034957 and 12606, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006953 and acute-phase response and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007584 and response to nutrient and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016032 and viral process and biological process this GO :0016363 and nuclear matrix and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0030099 and myeloid cell differentiation and biological process this GO :0030154 and cell differentiation and biological process this GO :0030225 and macrophage differentiation and biological process this GO :0030324 and lung development and biological process this GO :0031100 and organ regeneration and biological process this GO :0032403 and protein complex binding and molecular function this GO :0033274 and response to vitamin B2 and biological process this GO :0035189 and Rb-E2F complex and cellular component this GO :0042127 and regulation of cell proliferation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043234 and protein complex and cellular component this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045945 and positive regulation of transcription from RNA polymerase III promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048469 and cell maturation and biological process this GO :0048839 and inner ear development and biological process this GO :0050872 and white fat cell differentiation and biological process this GO :0050873 and brown fat cell differentiation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0071285 and cellular response to lithium ion and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071837 and HMG box domain binding and molecular function, HMG box domain binding, alpha, nuclei, this GO :0000050 and urea cycle and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001889 and liver development and biological process this GO :0001892 and embryonic placenta development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0006091 and generation of precursor metabolites and energy and biological process this GO :0006351 and transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019904 : protein domain specific binding and also this GO :0032403 : protein complex binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0071837 : HMG box domain binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019904 : protein domain specific binding, this GO :0032403 : protein complex binding, this GO :0042803 : protein homodimerization activity, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046982 : protein heterodimerization activity, this GO :0071837 : HMG box domain binding, CCAAT/enhancer binding protein (C/EBP) |
| Identity: |
1833 |
| Gene: |
CEBPA |
More about : CEBPA |
| Long gene name: |
CCAAT/enhancer binding protein alpha |
| Synonyms gene: |
CEBP |
| Synonyms gene name: |
CCAAT/enhancer binding protein (C/EBP), alpha |
| Synonyms: |
C/EBP-alpha |
| Locus: |
19q13, 11 |
| Discovery year: |
1991-11-27 |
| GenBank acession: |
M37197 |
| Entrez gene record: |
1050 |
| Pubmed identfication: |
1535333 1840554 |
| RefSeq identity: |
NM_004364 |
| Classification: |
CCAAT/enhancer binding proteins Basic leucine zipper proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000161461 |
| Locus Specific Databases: |
LRG_456 |