| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ANGPTL4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the ANGPTL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ANGPTL4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9BY76 |
| Purity: |
Purified |
| Description: |
Decreased expression of this protein has been associated with type 2 diabetes, The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness, This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells, lipid metabolism, secreted protein with a fibrinogen C-terminal domain, ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated |
| Immunogen: |
A portion of amino acids 138-167 from the human protein was used as the immunogen for this ANGPTL4 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ANGPTL4 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ANGPTL4 |
| Short name: |
ANGPTL4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
angiopoietin-like 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ANGPTL4 and IDBG-24662 and ENSG00000167772 and 51129, ANGPTL4 and IDBG-643821 and ENSBTAG00000002473 and 509963, Angptl4 and IDBG-167867 and ENSMUSG00000002289 and 57875, Extracellular, protein binding, this GO :0001525 and angiogenesis and biological process this GO :0001666 and response to hypoxia and biological process this GO :0004857 and enzyme inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0030154 and cell differentiation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0051005 and negative regulation of lipoprotein lipase activity and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0070328 and triglyceride homeostasis and biological process this GO :0072562 and blood microparticle and cellular component this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, this GO :0004857 : enzyme inhibitor activity, this GO :0004857 : enzyme inhibitor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, angiopoietin-like 4 |
| Identity: |
16039 |
| Gene: |
ANGPTL4 |
More about : ANGPTL4 |
| Long gene name: |
angiopoietin like 4 |
| Synonyms gene name: |
angiopoietin-like 4 |
| Synonyms: |
pp1158 PGAR ARP4 HFARP FIAF NL2 |
| Synonyms name: |
fasting-induced adipose factor hepatic angiopoietin-related protein PPARG angiopoietin related protein hepatic fibrinogen/angiopoietin-related protein peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein angiopoietin-related protein 4 |
| Locus: |
19p13, 2 |
| Discovery year: |
2001-07-18 |
| GenBank acession: |
AF202636 |
| Entrez gene record: |
51129 |
| Pubmed identfication: |
10698685 10866690 23960078 |
| RefSeq identity: |
NM_139314 |
| Classification: |
Fibrinogen C domain containing Angiopoietin like |
| Havana BLAST/BLAT: |
OTTHUMG00000182273 |