| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NAMPT |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the NAMPT antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This NAMPT antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P43490 |
| Purity: |
Antigen affinity |
| Description: |
It also activates insulin receptor and has insulin-mimetic effects, The protein is an adipokine that is localized to the bloodstream and has various functions, The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis, lowering blood glucose and improving insulin sensitivity, one step in the biosynthesis of nicotinamide adenine dinucleotide, NAMPT catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide |
| Immunogen: |
A portion of amino acids 400-426 from the human protein was used as the immunogen for this NAMPT antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NAMPT antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NAMPT |
| Short name: |
NAMPT Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
nicotinamide phosphoribosyltransferase (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
1110035O14Rik and PBEF and PBEF1 and VF and VISFATIN, BT, NAMPT and IDBG-35259 and ENSG00000105835 and 10135, Nampt and IDBG-134049 and ENSMUSG00000020572 and 59027, nicotinamide phosphoribosyltransferase activity, nuclei, this GO :0004514 and nicotinate-nucleotide diphosphorylase (carboxylating) activity and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006766 and vitamin metabolic process and biological process this GO :0006767 and water-soluble vitamin metabolic process and biological process this GO :0006769 and nicotinamide metabolic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007565 and female pregnancy and biological process this GO :0008144 and drug binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009435 and NAD biosynthetic process and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0019674 and NAD metabolic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0047280 and nicotinamide phosphoribosyltransferase activity and molecular function this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004514 : nicotinate-nucleotide diphosphorylase (carboxylating) activity, this GO :0004514 : nicotinate-nucleotide diphosphorylase (carboxylating) activity and also this GO :0005125 : cytokine activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding and also this GO :0042803 : protein homodimerization activity and also this GO :0047280 : nicotinamide phosphoribosyltransferase activity, this GO :0005125 : cytokine activity, this GO :0005515 : protein binding, this GO :0008144 : drug binding, this GO :0042803 : protein homodimerization activity, this GO :0047280 : nicotinamide phosphoribosyltransferase activity, 33608 and IDBG-632034 and ENSBTAG00000015509 and 520472, nicotinamide phosphoribosyltransferase |
| Identity: |
30092 |
| Gene: |
NAMPT |
More about : NAMPT |
| Long gene name: |
nicotinamide phosphoribosyltransferase |
| Synonyms gene: |
PBEF1 |
| Synonyms gene name: |
pre-B-cell colony enhancing factor 1 |
| Synonyms: |
PBEF |
| Synonyms name: |
visfatin |
| Locus: |
7q22, 3 |
| Discovery year: |
2004-02-02 |
| GenBank acession: |
U02020 |
| Entrez gene record: |
10135 |
| Pubmed identfication: |
8289818 |
| RefSeq identity: |
NM_182790 |
| Havana BLAST/BLAT: |
OTTHUMG00000140388 |