| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DGCR8 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the DGCR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This DGCR8 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8WYQ5 |
| Purity: |
Antigen affinity |
| Description: |
Post-transcriptional silencing of target genes by miRNAs occurs either by targeting specific cleavage of homologous mRNAs, Recent studies of miRNAs highlight a requirement for cell viability, or by targeting specific inhibition of protein synthesis, MicroRNAs (miRNA) are a recently discovered family of short non-protein-coding RNAs that negatively regulate gene expression |
| Immunogen: |
A portion of amino acids 439-466 from the human protein was used as the immunogen for this DGCR8 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DGCR8 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DGCR8 |
| Short name: |
DGCR8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DiGeorge syndrome critical region gene 8 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DGCR8 and IDBG-1583 and ENSG00000128191 and 100302197, DGCR8 and IDBG-638235 and ENSBTAG00000019869 and 540254, Dgcr8 and IDBG-141484 and ENSMUSG00000022718 and 94223, metal ion binding, nuclei, this GO :0003725 and double-stranded RNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0010467 and gene expression and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0031053 and primary miRNA processing and biological process this GO :0046872 and metal ion binding and molecular function, this GO :0003725 : double-stranded RNA binding, this GO :0003725 : double-stranded RNA binding and also this GO :0005515 : protein binding and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0046872 : metal ion binding, 54487, DiGeorge syndrome critical region gene 8 |
| Identity: |
2847 |
| Gene: |
DGCR8 |
More about : DGCR8 |
| Long gene name: |
DGCR8, microprocessor complex subunit |
| Synonyms gene: |
C22orf12 |
| Synonyms gene name: |
chromosome 22 open reading frame 12 DiGeorge syndrome critical region gene 8 |
| Synonyms: |
DGCRK6 Gy1 pasha |
| Locus: |
22q11, 21 |
| Discovery year: |
2000-06-29 |
| GenBank acession: |
AF165527 AB050770 |
| Entrez gene record: |
54487 |
| Pubmed identfication: |
21454614 |
| Havana BLAST/BLAT: |
OTTHUMG00000150503 |