| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ALK1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the ALK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ALK1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P37023 |
| Purity: |
Purified |
| Description: |
It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, Mutations in this gene are associated with hemorrhagic telangiectasia type 2, This protein, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, also known as Rendu-Osler-Weber syndrome 2, and a short C-terminal tail, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases, sometimes termed ALK1, ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands |
| Immunogen: |
A portion of amino acids 38-68 from the human protein was used as the immunogen for this ALK1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ALK1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ALK1 |
| Short name: |
ALK1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ALK1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
175 |
| Gene: |
ACVRL1 |
More about : ACVRL1 |
| Long gene name: |
activin A receptor like type 1 |
| Synonyms gene: |
ACVRLK1 ORW2 |
| Synonyms gene name: |
activin A receptor type II-like 1 activin A receptor type IL |
| Synonyms: |
HHT2 ALK1 HHT |
| Locus: |
12q13, 13 |
| Discovery year: |
1994-12-12 |
| GenBank acession: |
L17075 |
| Entrez gene record: |
94 |
| Pubmed identfication: |
8397373 8640225 22718755 |
| RefSeq identity: |
NM_000020 |
| Classification: |
Type 1 receptor serine/threonine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000169507 |
| Locus Specific Databases: |
Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database LRG_543 |