| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ALK2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the ALK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ALK2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q04771 |
| Purity: |
Purified |
| Description: |
ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors, Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors, These receptors are all transmembrane proteins, Type I and II receptors form a stable complex after ligand binding, Type I receptors are essential for signaling, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity, and type II receptors are required for binding ligands and for expression of type I receptors, composed of a ligand-binding extracellular domain with cysteine-rich region, resulting in phosphorylation of type I receptors by type II receptors, Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins |
| Immunogen: |
A portion of amino acids 132-162 from the human protein was used as the immunogen for this ALK2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ALK2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ALK2 |
| Short name: |
ALK2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ALK2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
171 |
| Gene: |
ACVR1 |
More about : ACVR1 |
| Long gene name: |
activin A receptor type 1 |
| Synonyms gene: |
ACVRLK2 |
| Synonyms gene name: |
activin A receptor, type I |
| Synonyms: |
SKR1 ALK2 ACVR1A |
| Locus: |
2q24, 1 |
| Discovery year: |
1994-01-10 |
| Entrez gene record: |
90 |
| Pubmed identfication: |
8397373 |
| RefSeq identity: |
NM_001105 |
| Classification: |
Type 1 receptor serine/threonine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000131967 |