| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ACE |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the ACE antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ACE antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P12821 |
| Purity: |
Purified |
| Description: |
Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance, Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies, This enzyme plays a key role in the renin-angiotensin system, Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active, ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II |
| Immunogen: |
A portion of amino acids 1274-1306 from the human protein was used as the immunogen for this ACE antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ACE antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ACE |
| Short name: |
ACE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Uncharacterized protein (Antibody to), Angiotensin-converting enzyme |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ACE and IDBG-728302 and ENSG00000264813 and, Plasma membranes, Uncharacterized protein, peptidyl-dipeptidase activity, this GO :0006508 and proteolysis and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008241 and peptidyl-dipeptidase activity and molecular function this GO :0016020 and membrane and cellular component, this GO :0008237 : metallopeptidase activity, this GO :0008237 : metallopeptidase activity and also this GO :0008241 : peptidyl-dipeptidase activity, this GO :0008241 : peptidyl-dipeptidase activity, Angiotensin-converting enzyme |
| Identity: |
2707 |
| Gene: |
ACE |
More about : ACE |
| Long gene name: |
angiotensin I converting enzyme |
| Synonyms gene: |
DCP1 |
| Synonyms gene name: |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
| Synonyms: |
ACE1 CD143 |
| Synonyms name: |
peptidyl-dipeptidase A |
| Locus: |
17q23, 3 |
| Discovery year: |
1989-06-06 |
| GenBank acession: |
J04144 |
| Entrez gene record: |
1636 |
| Pubmed identfication: |
2554286 10319862 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000154927 |