| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FKBP12 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the FKBP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This FKBP12 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P62942 |
| Purity: |
Purified |
| Description: |
In mouse, It also interacts with multiple intracellular calcium release channels, It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor, The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking, FKBP12 is a member of the immunophilin protein family |
| Immunogen: |
A portion of amino acids 43-74 from the human protein was used as the immunogen for this FKBP12 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the FKBP12 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FKBP12 |
| Short name: |
FKBP12 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FKBP12 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3711 |
| Gene: |
FKBP1A |
More about : FKBP1A |
| Long gene name: |
FK506 binding protein 1A |
| Synonyms gene: |
FKBP1 |
| Synonyms gene name: |
12kDa , FK506-binding protein 1A (12kD) FK506 binding protein 1A |
| Synonyms: |
FKBP-12 FKBP12 PKC12 PPIASE FKBP12C |
| Synonyms name: |
calstabin 1 |
| Locus: |
20p13 |
| Discovery year: |
1992-09-14 |
| GenBank acession: |
M92423 |
| Entrez gene record: |
2280 |
| Pubmed identfication: |
1930186 |
| Classification: |
FKBP prolyl isomerases |
| Havana BLAST/BLAT: |
OTTHUMG00000031666 |