| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PDGFR alpha |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the PDGFR alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PDGFR alpha antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P16234 |
| Purity: |
Antigen affinity |
| Description: |
Studies in knockout mice, The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, These growth factors are mitogens for cells of mesenchymal origin, composed of both platelet-derived growth factor receptor alpha and beta polypeptides, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes, where homozygosity is lethal, PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family |
| Immunogen: |
A portion of amino acids 740-769 from the human protein was used as the immunogen for this PDGFR alpha antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PDGFR alpha antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PDGFR alpha |
| Short name: |
PDGFR alpha Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PDGFR a (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8804 |
| Gene: |
PDGFRB |
More about : PDGFRB |
| Long gene name: |
platelet derived growth factor receptor beta |
| Synonyms gene: |
PDGFR |
| Synonyms gene name: |
beta polypeptide , platelet-derived growth factor receptor |
| Synonyms: |
JTK12 CD140b PDGFR1 |
| Locus: |
5q32 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M21616 |
| Entrez gene record: |
5159 |
| RefSeq identity: |
NM_002609 |
| Classification: |
I-set domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000130053 |