| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD135 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the CD135 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CD135 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P36888 |
| Purity: |
Purified |
| Description: |
58 are of receptor protein TK (e, ABL, By this basic mechanism, EGFR, EPH, FAK, FGFR, JAK, PDGFR, TRK, The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains, The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, There are currently about 90 TK genes sequenced, With more than 500 gene products, adhesion, and 32 of cytosolic TK (e, and SRC families), and VEGFR families), and differentiation, apoptosis, cell cycle progression, cytoskeletal rearrangement and cell movement, generally the g phosphate of ATP, motility and death, onto an acceptor amino acid in a substrate protein, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, the protein kinase family is one of the largest families of proteins in eukaryotes, transcription, Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, g, g |
| Immunogen: |
A portion of amino acids 951-982 from the human protein was used as the immunogen for this CD135 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD135 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD135 |
| Short name: |
CD135 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD135 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3765 |
| Gene: |
FLT3 |
More about : FLT3 |
| Long gene name: |
fms related tyrosine kinase 3 |
| Synonyms gene name: |
fms-related tyrosine kinase 3 |
| Synonyms: |
STK1 FLK2 CD135 |
| Locus: |
13q12, 2 |
| Discovery year: |
1990-07-30 |
| GenBank acession: |
U02687 |
| Entrez gene record: |
2322 |
| Pubmed identfication: |
8394751 |
| Classification: |
CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000016646 |
| Locus Specific Databases: |
LRG_457 |