| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Eph Receptor B2 (EphB2) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:100 |
| Notes: |
Titration of the EphB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This EphB2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P29323 |
| Purity: |
Purified |
| Description: |
Based on their structures and sequence relationships, Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family, It binds RASGAP through the juxtamembrane tyrosines residues, It is preferentially expressed in fetal brain, The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands, The ligand-activated form of EphB2, This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, and the ephrin-B (EFNB) class, ephrins are divided into the ephrin-A (EFNA) class, heart, including GTPase-activating protein (RASGAP) through its SH2 domain, interacts with multiple proteins, kidney, liver and skeletal muscle, lung, mediate numerous developmental processes, pancreas, particularly in the nervous system, placenta, the ephrins, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, which are transmembrane proteins, which belongs to the Tyr family of protein kinases, Ephrin receptors and their ligands |
| Immunogen: |
A portion of amino acids 103-133 from the human protein was used as the immunogen for this EphB2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the EphB2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Eph Receptor B2 (EphB2) |
| Short name: |
Eph Receptor B2 Antibody (EphB2) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Eph Receptor B2 (Antibody to) (EphB2) |
| Alternative technique: |
antibodies |