| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ApoE (Apolipoprotein E) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IHC |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the ApoE antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ApoE antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P02649 |
| Purity: |
Antigen affinity |
| Description: |
ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents, Apolipoprotein E, Defects in apolipoprotein E result in familial dysbetalipoproteinemia, The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells, or type III hyperlipoproteinemia (HLP III), Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver, in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants |
| Immunogen: |
A portion of amino acids 263-292 from the human protein was used as the immunogen for this ApoE antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ApoE antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ApoE (Apolipoprotein E) |
| Short name: |
ApoE Antibody (Apolipoprotein E) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
apolipoprotein E (Antibody to) (Apolipoprotein E) |
| Alternative technique: |
antibodies |