| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AKT2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IF, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the AKT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This AKT2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P31751 |
| Purity: |
Antigen affinity |
| Description: |
AKT2 has been shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors, AKT2 is a general protein kinase capable of phophorylating several known proteins, Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers, AKT2 is a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains |
| Immunogen: |
A portion of amino acids 452-481 from the human protein was used as the immunogen for this AKT2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AKT2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AKT2 |
| Short name: |
AKT2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
v-akt murine thymoma viral oncogene homolog 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AKT2 and IDBG-51270 and ENSG00000105221 and 208, AKT2 and IDBG-637808 and ENSBTAG00000001400 and 534923, Akt2 and IDBG-161456 and ENSMUSG00000004056 and 11652, HIHGHH and PKBB and PKBBETA and PRKBB and RAC-BETA, nuclei, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0005978 and glycogen biosynthetic process and biological process this GO :0006006 and glucose metabolic process and biological process this GO :0006417 and regulation of translation and biological process this GO :0006464 and cellular protein modification process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008643 and carbohydrate transport and biological process this GO :0010748 and negative regulation of plasma membrane long-chain fatty acid transport and biological process this GO :0010907 and positive regulation of glucose metabolic process and biological process this GO :0016301 and kinase activity and molecular function this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0030334 and regulation of cell migration and biological process this GO :0031340 and positive regulation of vesicle fusion and biological process this GO :0032000 and positive regulation of fatty acid beta-oxidation and biological process this GO :0032287 and peripheral nervous system myelin maintenance and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032859 and activation of Ral GTPase activity and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0061024 and membrane organization and biological process this GO :0065002 and intracellular protein transmembrane transport and biological process this GO :0071156 and regulation of cell cycle arrest and biological process this GO :0072659 and protein localization to plasma membrane and biological process this GO :0090314 and positive regulation of protein targeting to membrane and biological process this GO :2000147 and positive regulation of cell motility and biological process this GO :2001275 and positive regulation of glucose import in response to insulin stimulus and biological process, v-akt murine thymoma viral oncogene homolog 2 |
| Identity: |
392 |
| Gene: |
AKT2 |
More about : AKT2 |
| Long gene name: |
AKT serine/threonine kinase 2 |
| Synonyms gene name: |
v-akt murine thymoma viral oncogene homolog 2 |
| Locus: |
19q13, 2 |
| Discovery year: |
1992-11-05 |
| GenBank acession: |
M77198 |
| Entrez gene record: |
208 |
| Pubmed identfication: |
1409633 |
| RefSeq identity: |
NM_001626 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000137375 |