Aurora-A Antibody (AURKA)

Catalog number:	F50015-0.08ML Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Aurora-A Antibody (AURKA)
Quantity:	0.1ml
Other quantities:	0.08 ml 199€
Related search:	auroraa kinase gene antibodies synonyms stk frozen

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Category:	Antibody
Concentration:	pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form:	Purified
Conjugation:	Unconjugated
Clone:	Polyclonal antibody
Recognised antigen:	Aurora-A (AURKA)
Host animal:	Rabbit (Oryctolagus cuniculus)
Clonality:	Polyclonal (rabbit origin)
Species reactivity:	Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications:	ELISA, FACS, IF, WB
Recommended dilutions:	Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes:	Titration of the Aurora-A antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use:	This Aurora-A antibodyis to be used only for research purposes and not for diagnostics
Uniprot #:	O14965
Purity:	Purified
Description:	Aurora kinase A localizes on centrosomes in interphase cells and at each spindle pole in mitosis, Auroria kinase A may play a role in cell cycle regulation during anaphase and/or telophase, Defects in Aurora kinase A are responsible for numerical centrosome aberrations including aneuploidy, Expression is cell-cycle regulated, It is highly expressed in testis, It may be involved in microtubule formation and/or stabilization, The Aurora kinases, This protein has also been postulated to play a key role during tumor development and progression, accumulates during G2/M, and also highly expressed in colon, and decreases rapidly afterward, associate with microtubules during chromosome movement and segregation, breast and cervical cancer cell lines, in relation to the function of the centrosome/spindle pole region during chromosome segregation, low in G1/S, members of the Ser/Thr protein kinase family, neuroblastoma, ovarian, prostate, thymus and spleen, weakly in skeletal muscle, Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases
Immunogen:	A portion of amino acids 364-392 from the human protein was used as the immunogen for this Aurora-A antibody
Storage:	Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Aurora-A antibody and store frozen at -20 deg
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target:	Aurora-A (AURKA)
Short name:	Aurora-A Antibody (AURKA)
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	Aurora-A (Antibody to) (AURKA)
Alternative technique:	antibodies
Identity:	11393
Gene:	AURKA | More about : AURKA
Long gene name:	aurora kinase A
Synonyms gene:	STK15 STK6
Synonyms gene name:	serine/threonine kinase 15 serine/threonine kinase 6
Synonyms:	BTAK AurA STK7 ARK1 PPP1R47 AIK
Synonyms name:	protein phosphatase 1, regulatory subunit 47 Aurora-A kinase
Locus:	20q13, 2
Discovery year:	1998-10-02
GenBank acession:	BC001280
Entrez gene record:	6790
Pubmed identfication:	9174055 9771714
RefSeq identity:	NM_003600
Classification:	Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT:	OTTHUMG00000032796

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