| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
LAG3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the LAG3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This LAG3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P18627 |
| Purity: |
Antigen affinity |
| Description: |
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains |
| Immunogen: |
A portion of amino acids 103-132 from the human protein was used as the immunogen for this LAG3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the LAG3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
LAG3 |
| Short name: |
LAG3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
lymphocyte-activation gene 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CD223, Cell surfaces, LAG3 and IDBG-14994 and ENSG00000089692 and 3902, Lag3 and IDBG-188462 and ENSMUSG00000030124 and 16768, MHC class II protein binding, this GO :0003823 and antigen binding and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0042289 and MHC class II protein binding and molecular function this GO :0045085 and negative regulation of interleukin-2 biosynthetic process and biological process this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process this GO :0050868 and negative regulation of T cell activation and biological process, this GO :0003823 : antigen binding, this GO :0003823 : antigen binding and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0042289 : MHC class II protein binding, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0042289 : MHC class II protein binding, 18959 and IDBG-640276 and ENSBTAG00000034295 and 515155, lymphocyte-activation gene 3 |
| Identity: |
6476 |
| Gene: |
LAG3 |
More about : LAG3 |
| Long gene name: |
lymphocyte activating 3 |
| Synonyms gene name: |
lymphocyte-activation gene 3 |
| Synonyms: |
CD223 |
| Locus: |
12p13, 31 |
| Discovery year: |
1991-06-03 |
| Entrez gene record: |
3902 |
| RefSeq identity: |
NM_002286 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000169197 |