| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ANGPTL3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the ANGPTL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ANGPTL3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y5C1 |
| Purity: |
Purified |
| Description: |
It is predominantly expressed in the liver, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain, The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, This protein may also play a role in the regulation of angiogenesis, and has the characteristic structure of angiopoietins, and this binding induced endothelial cell adhesion and migration, consisting of a signal peptide, ANGPTL3 is a member of the angiopoietin-like family of secreted factors |
| Immunogen: |
A portion of amino acids 82-114 from the human protein was used as the immunogen for this ANGPTL3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ANGPTL3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ANGPTL3 |
| Short name: |
ANGPTL3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
angiopoietin-like 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ANGPTL3 and IDBG-638594 and ENSBTAG00000021386 and 782603, ANGPTL3 and IDBG-99367 and ENSG00000132855 and 27329, Angptl3 and IDBG-166252 and ENSMUSG00000028553 and 30924, Extracellular, growth factor activity, this GO :0004857 and enzyme inhibitor activity and molecular function this GO :0004859 and phospholipase inhibitor activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006071 and glycerol metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0009395 and phospholipid catabolic process and biological process this GO :0009725 and response to hormone and biological process this GO :0009986 and cell surface and cellular component this GO :0010519 and negative regulation of phospholipase activity and biological process this GO :0019915 and lipid storage and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0050996 and positive regulation of lipid catabolic process and biological process this GO :0051005 and negative regulation of lipoprotein lipase activity and biological process this GO :0055088 and lipid homeostasis and biological process this GO :0055090 and acylglycerol homeostasis and biological process this GO :0055091 and phospholipid homeostasis and biological process this GO :0070328 and triglyceride homeostasis and biological process, this GO :0004857 : enzyme inhibitor activity, this GO :0004857 : enzyme inhibitor activity and also this GO :0004859 : phospholipase inhibitor activity and also this GO :0005178 : integrin binding and also this GO :0008083 : growth factor activity, this GO :0004859 : phospholipase inhibitor activity, this GO :0005178 : integrin binding, this GO :0008083 : growth factor activity, angiopoietin-like 3 |
| Identity: |
491 |
| Gene: |
ANGPTL3 |
More about : ANGPTL3 |
| Long gene name: |
angiopoietin like 3 |
| Synonyms gene: |
ANGPT5 |
| Synonyms gene name: |
angiopoietin-like 3 |
| Synonyms name: |
angiopoietin 5 |
| Locus: |
1p31, 3 |
| Discovery year: |
2000-02-07 |
| GenBank acession: |
AF152562 |
| Entrez gene record: |
27329 |
| Pubmed identfication: |
10644446 |
| RefSeq identity: |
NM_014495 |
| Classification: |
Fibrinogen C domain containing Angiopoietin like |
| Havana BLAST/BLAT: |
OTTHUMG00000009146 |