| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
WNT4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the WNT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This WNT4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P56705 |
| Purity: |
Purified |
| Description: |
It play a concerted role in both the control of female development and the prevention of testes formation, These proteins have been implicated in oncogenesis and in several developmental processes, WNT4 is a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat, including regulation of cell fate and patterning during embryogenesis, The WNT family consists of secreted signaling proteins |
| Immunogen: |
A portion of amino acids 211-239 from the human protein was used as the immunogen for this WNT4 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the WNT4 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
WNT4 |
| Short name: |
WNT4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 4 (Antibody to), wingless-classification MMTV integration site family |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0048018 and receptor a this GO nist activity and molecular function this GO :0048599 and oocyte development and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0048856 and anatomical structure development and biological process this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0051894 and positive regulation of focal adhesion assembly and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060126 and somatotropin secreting cell differentiation and biological process this GO :0060129 and thyroid-stimulating hormone-secreting cell differentiation and biological process this GO :0060231 and mesenchymal to epithelial transition and biological process this GO :0060748 and tertiary branching involved in mammary gland duct morphogenesis and biological process this GO :0060993 and kidney morphogenesis and biological process this GO :0061045 and negative regulation of wound healing and biological process this GO :0061180 and mammary gland epithelium development and biological process this GO :0061184 and positive regulation of dermatome development and biological process this GO :0061205 and paramesonephric duct development and biological process this GO :0061369 and negative regulation of testicular blood vessel morphogenesis and biological process this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process this GO :0072033 and renal vesicle formation and biological process this GO :0072034 and renal vesicle induction and biological process this GO :0072162 and metanephric mesenchymal cell differentiation and biological process this GO :0072164 and mesonephric tubule development and biological process this GO :0072174 and metanephric tubule formation and biological process this GO :0072210 and metanephric nephron development and biological process this GO :0072273 and metanephric nephron morphogenesis and biological process this GO :0090002 and establishment of protein localization to plasma membrane and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :2000019 and negative regulation of male this GO nad development and biological process this GO :2000066 and positive regulation of cortisol biosynthetic process and biological process this GO :2000225 and negative regulation of testosterone biosynthetic process and biological process this GO :2001234 and negative regulation of apoptotic signaling pathway and biological process, Extracellular, WNT4 and IDBG-645527 and ENSBTAG00000022671 and 789600, WNT4 and IDBG-93664 and ENSG00000162552 and 54361, Wnt4 and IDBG-198435 and ENSMUSG00000036856 and 22417, member 4, receptor a this GO nist activity, this GO :0001656 and metanephros development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001822 and kidney development and biological process this GO :0001823 and mesonephros development and biological process this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0001838 and embryonic epithelial tube formation and biological process this GO :0001889 and liver development and biological process this GO :0003714 and transcription corepressor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005109 and frizzled binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005796 and this GO lgi lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006702 and androgen biosynthetic process and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007276 and gamete generation and biological process this GO :0007548 and sex differentiation and biological process this GO :0008584 and male this GO nad development and biological process this GO :0008585 and female this GO nad development and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0009986 and cell surface and cellular component this GO :0010629 and negative regulation of gene expression and biological process this GO :0010894 and negative regulation of steroid biosynthetic process and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0018345 and protein palmitoylation and biological process this GO :0022407 and regulation of cell-cell adhesion and biological process this GO :0030154 and cell differentiation and biological process this GO :0030182 and neuron differentiation and biological process this GO :0030237 and female sex determination and biological process this GO :0030325 and adrenal gland development and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032349 and positive regulation of aldosterone biosynthetic process and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033080 and immature T cell proliferation in thymus and biological process this GO :0035239 and tube morphogenesis and biological process this GO :0035567 and non-canonical Wnt signaling pathway and biological process this GO :0038030 and non-canonical Wnt receptor signaling pathway via MAPK cascade and biological process this GO :0040037 and negative regulation of fibroblast growth factor receptor signaling pathway and biological process this GO :0042445 and hormone metabolic process and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045836 and positive regulation of meiosis and biological process this GO :0045892 and negative regulation of transcription, this GO :0003714 : transcription corepressor activity, this GO :0003714 : transcription corepressor activity and also this GO :0005102 : receptor binding and also this GO :0005109 : frizzled binding and also this GO :0005515 : protein binding and also this GO :0048018 : receptor a this GO nist activity, this GO :0005102 : receptor binding, this GO :0005109 : frizzled binding, this GO :0005515 : protein binding, this GO :0048018 : receptor a this GO nist activity, wingless-type MMTV integration site family |
| Identity: |
12783 |
| Gene: |
WNT4 |
More about : WNT4 |
| Long gene name: |
Wnt family member 4 |
| Synonyms gene name: |
member 4 , wingless-type MMTV integration site family |
| Synonyms: |
WNT-4 |
| Locus: |
1p36, 12 |
| Discovery year: |
2000-07-31 |
| GenBank acession: |
AL031281 |
| Entrez gene record: |
54361 |
| Pubmed identfication: |
8168088 |
| Classification: |
Wnt family Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000002894 |