| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
WNT10B |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the WNT10B antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This WNT10B antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O00744 |
| Purity: |
Purified |
| Description: |
It may be involved in breast cancer, These proteins have been implicated in oncogenesis and in several developmental processes, This protein is 96% identical to the mouse Wnt10b protein at the amino acid level, WNT10B is a member of the WNT family, and its protein signaling is likely a molecular switch that governs adipogenesis, including regulation of cell fate and patterning during embryogenesis, The WNT gene family consists of structurally related genes which encode secreted signaling proteins |
| Immunogen: |
A portion of amino acids 193-222 from the human protein was used as the immunogen for this WNT10B antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the WNT10B antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
WNT10B |
| Short name: |
WNT10B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 10B (Antibody to), wingless-classification MMTV integration site family |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, SHFM6 and WNT-12, WNT10B and IDBG-30678 and ENSG00000169884 and 7480, WNT10B and IDBG-632758 and ENSBTAG00000015347 and, Wnt10b and IDBG-181195 and ENSMUSG00000022996 and 22410, member 10B, receptor a this GO nist activity, this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0002062 and chondrocyte differentiation and biological process this GO :0005102 and receptor binding and molecular function this GO :0005109 and frizzled binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006629 and lipid metabolic process and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0010971 and positive regulation of G2/M transition of mitotic cell cycle and biological process this GO :0014835 and myoblast differentiation involved in skeletal muscle regeneration and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0030182 and neuron differentiation and biological process this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0030858 and positive regulation of epithelial cell differentiation and biological process this GO :0032434 and regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045598 and regulation of fat cell differentiation and biological process this GO :0045599 and negative regulation of fat cell differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045778 and positive regulation of ossification and biological process this GO :0045899 and positive regulation of RNA polymerase II transcriptional preinitiation complex assembly and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048018 and receptor a this GO nist activity and molecular function this GO :0048641 and regulation of skeletal muscle tissue development and biological process this GO :0048741 and skeletal muscle fiber development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050821 and protein stabilization and biological process this GO :0050909 and sensory perception of taste and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051246 and regulation of protein metabolic process and biological process this GO :0051885 and positive regulation of anagen and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060346 and bone trabecula formation and biological process this GO :0061196 and fungiform papilla development and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0071310 and cellular response to organic substance and biological process this GO :0071320 and cellular response to cAMP and biological process this GO :0071374 and cellular response to parathyroid hormone stimulus and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071425 and hematopoietic stem cell proliferation and biological process this GO :0071464 and cellular response to hydrostatic pressure and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005109 : frizzled binding and also this GO :0048018 : receptor a this GO nist activity, this GO :0005109 : frizzled binding, this GO :0048018 : receptor a this GO nist activity, wingless-type MMTV integration site family |
| Identity: |
12775 |
| Gene: |
WNT10B |
More about : WNT10B |
| Long gene name: |
Wnt family member 10B |
| Synonyms gene name: |
member 10B , wingless-type MMTV integration site family |
| Synonyms: |
WNT-12 SHFM6 |
| Locus: |
12q13, 12 |
| Discovery year: |
1997-09-05 |
| GenBank acession: |
X97057 |
| Entrez gene record: |
7480 |
| Pubmed identfication: |
9121776 9284937 18515319 |
| RefSeq identity: |
NM_003394 |
| Classification: |
Wnt family |
| Havana BLAST/BLAT: |
OTTHUMG00000150734 |