| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Glypican 3 (GPC3) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IF |
| Recommended dilutions: |
Immunofluorescence: Tested, Western blot: 1:1000 |
| Notes: |
Titration of the Glypican 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Glypican 3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P51654 |
| Purity: |
Purified |
| Description: |
Inhibits the dipeptidyl peptidase activity of DPP4, May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function, May regulate growth and tumor predisposition, [UniProt], Cell surface proteoglycan that bears heparan sulfate |
| Immunogen: |
A portion of amino acids 335-365 from the human protein was used as the immunogen for this Glypican 3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Glypican 3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Glypican 3 (GPC3) |
| Short name: |
Glypican 3 Antibody (GPC3) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Glypican 3 (Antibody to) (glypican 3) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DGSX and GTR2-2 and MXR7 and OCI-5 and SDYS and SGB and SGBS and SGBS1, Extracellular, GPC3 and IDBG-630953 and ENSBTAG00000020406 and 615239, GPC3 and IDBG-86754 and ENSG00000147257 and 2719, Gpc3 and IDBG-145213 and ENSMUSG00000055653 and 14734, peptidyl-dipeptidase inhibitor activity, planar cell polarity pathway and biological process, this GO :0001523 and retinoid metabolic process and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001822 and kidney development and biological process this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005764 and lysosome and cellular component this GO :0005796 and this GO lgi lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006024 and glycosaminoglycan biosynthetic process and biological process this GO :0006027 and glycosaminoglycan catabolic process and biological process this GO :0007603 and phototransduction, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0043395 : heparan sulfate proteoglycan binding and also this GO :0060422 : peptidyl-dipeptidase inhibitor activity, this GO :0043395 : heparan sulfate proteoglycan binding, this GO :0060422 : peptidyl-dipeptidase inhibitor activity, visible light and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009948 and anterior/posterior axis specification and biological process this GO :0010171 and body morphogenesis and biological process this GO :0010466 and negative regulation of peptidase activity and biological process this GO :0016020 and membrane and cellular component this GO :0030203 and glycosaminoglycan metabolic process and biological process this GO :0030204 and chondroitin sulfate metabolic process and biological process this GO :0030282 and bone mineralization and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0030324 and lung development and biological process this GO :0030513 and positive regulation of BMP signaling pathway and biological process this GO :0035116 and embryonic hindlimb morphogenesis and biological process this GO :0040008 and regulation of growth and biological process this GO :0043202 and lysosomal lumen and cellular component this GO :0043395 and heparan sulfate proteoglycan binding and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045807 and positive regulation of endocytosis and biological process this GO :0045879 and negative regulation of smoothened signaling pathway and biological process this GO :0045880 and positive regulation of smoothened signaling pathway and biological process this GO :0045926 and negative regulation of growth and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0046658 and anchored component of plasma membrane and cellular component this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0060422 and peptidyl-dipeptidase inhibitor activity and molecular function this GO :0060976 and coronary vasculature development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072111 and cell proliferation involved in kidney development and biological process this GO :0072138 and mesenchymal cell proliferation involved in ureteric bud development and biological process this GO :0072180 and mesonephric duct morphogenesis and biological process this GO :0072203 and cell proliferation involved in metanephros development and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :2000096 and positive regulation of Wnt receptor signaling pathway, glypican 3 |
| Identity: |
4451 |
| Gene: |
GPC3 |
More about : GPC3 |
| Long gene name: |
glypican 3 |
| Synonyms gene: |
SDYS |
| Synonyms: |
OCI-5 SGBS SGBS1 SGB DGSX |
| Synonyms name: |
glypican proteoglycan 3 |
| Locus: |
Xq26, 2 |
| Discovery year: |
1996-08-08 |
| GenBank acession: |
L47125 |
| Entrez gene record: |
2719 |
| Pubmed identfication: |
8589713 9787072 |
| RefSeq identity: |
NM_004484 |
| Classification: |
Glypicans |
| Havana BLAST/BLAT: |
OTTHUMG00000022448 |
| Locus Specific Databases: |
LRG_505 |