| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CUX1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IF, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the CUX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CUX1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P39880 |
| Purity: |
Antigen affinity |
| Description: |
Binds to the TH enhancer, Component of nf-munr repressor, May act by preventing binding of positively-activing CCAAT factors to promoters, Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, [UniProt], an ATC-rich DNA sequence located upstream of the TCR beta enhancer, binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer, may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity), CUX1 likely has a broad role in mammalian development as a repressor of developmentally regulated gene expression |
| Immunogen: |
A portion of amino acids 1347-1374 from the human protein was used as the immunogen for this CUX1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CUX1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CUX1 |
| Short name: |
CUX1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CUX1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2557 |
| Gene: |
CUX1 |
More about : CUX1 |
| Long gene name: |
cut like homeobox 1 |
| Synonyms gene: |
CUTL1 |
| Synonyms gene name: |
CCAAT displacement protein (Drosophila) cut-like homeobox 1 , cut (Drosophila)-like 1 (CCAAT displacement protein) cut-like 1 |
| Synonyms: |
CDP CDP1 CUX CUT Clox CDP/Cut CDP/Cux Cux/CDP CASP GOLIM6 |
| Synonyms name: |
golgi integral membrane protein 6 |
| Locus: |
7q22, 1 |
| Discovery year: |
1992-12-13 |
| GenBank acession: |
M74099 |
| Entrez gene record: |
1523 |
| Pubmed identfication: |
8468066 9799793 15004235 |
| RefSeq identity: |
NM_001913 |
| Classification: |
CUT class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000157129 |