| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TREM2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the TREM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This TREM2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9NZC2 |
| Purity: |
Antigen affinity |
| Description: |
Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells, [UniProt], TREM2 may have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines |
| Immunogen: |
A portion of amino acids 22-50 from the human protein was used as the immunogen for this TREM2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TREM2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TREM2 |
| Short name: |
TREM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
triggering receptor expressed on myeloid cells 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, TREM2 and IDBG-630863 and ENSBTAG00000007275 and 506467, TREM2 and IDBG-86566 and ENSG00000095970 and 54209, Trem2 and IDBG-189871 and ENSMUSG00000023992 and 83433, scaffold protein binding, this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0002588 and positive regulation of antigen processing and presentation of peptide antigen via MHC class II and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006959 and humoral immune response and biological process this GO :0007411 and axon guidance and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0045087 and innate immune response and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0097028 and dendritic cell differentiation and biological process this GO :0097110 and scaffold protein binding and molecular function this GO :1903078 and positive regulation of protein localization to plasma membrane and biological process this GO :1903082 and positive regulation of C-C chemokine receptor CCR7 signaling pathway and biological process this GO :2000350 and positive regulation of CD40 signaling pathway and biological process, this GO :0001530 : lipopolysaccharide binding, this GO :0001530 : lipopolysaccharide binding and also this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0097110 : scaffold protein binding, this GO :0004872 : receptor activity, this GO :0005515 : protein binding, this GO :0097110 : scaffold protein binding, triggering receptor expressed on myeloid cells 2 |
| Identity: |
17761 |
| Gene: |
TREM2 |
More about : TREM2 |
| Long gene name: |
triggering receptor expressed on myeloid cells 2 |
| Synonyms gene name: |
triggering receptor expressed on myeloid cells 2a |
| Synonyms: |
TREM-2 Trem2a Trem2b Trem2c |
| Locus: |
6p21, 1 |
| Discovery year: |
2002-08-09 |
| GenBank acession: |
AF213457 |
| Entrez gene record: |
54209 |
| Pubmed identfication: |
10799849 12080485 |
| RefSeq identity: |
NM_018965 |
| Classification: |
V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000014671 |
| Locus Specific Databases: |
LRG_631 |