| Catalog number: | F49022-0.4ML |
|---|---|
| Price: | 470 € |
| Supplier: | MBS Polyclonals |
| Product name: | ATF6 beta Antibody |
| Quantity: | 100ug |
| Other quantities: | 0.08 ml 199€ 0.1ml 263€ |
| Related search: |
| Category: | Antibody |
|---|---|
| Concentration: | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | ATF6 beta |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, Hamster, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: | ELISA, WB, IHC |
| Recommended dilutions: | IHC (Paraffin): 1:25, Western blot: 1:1000 |
| Notes: | Titration of the ATF6 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: | This ATF6 beta antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: | Q99941 |
| Purity: | Antigen affinity |
| Description: | Either as a homodimer or as a heterodimer with ATF6-alpha, The protein is normally found in the membrane of the endoplasmic reticulum, however, interacting with nuclear transcription factor Y to activate UPR target genes, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus, the encoded protein binds to the ER stress response element, under ER stress, ATF6 beta is a transcription factor in the unfolded protein response (UPR) pathway during ER stress |
| Immunogen: | A portion of amino acids 560-589 from the human protein was used as the immunogen for this ATF6 beta antibody |
| Storage: | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ATF6 beta antibody and store frozen at -20 deg |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | ATF6 beta |
| Short name: | ATF6 beta Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | ATF6 b (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 791 |
| Gene: | ATF6 | More about : ATF6 |
| Long gene name: | activating transcription factor 6 |
| Synonyms: | ATF6A |
| Synonyms name: | activating transcription factor 6 alpha |
| Locus: | 1q23, 3 |
| Discovery year: | 1999-12-15 |
| GenBank acession: | AB015856 |
| Entrez gene record: | 22926 |
| Pubmed identfication: | 9837962 9271374 11256944 |
| RefSeq identity: | NM_007348 |
| Classification: | Basic leucine zipper proteins |
| Havana BLAST/BLAT: | OTTHUMG00000023961 |
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