| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CA9 (Carbonic Anhydrase IX) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the CA9 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CA9 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q16790 |
| Purity: |
Purified |
| Description: |
CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known, It is expressed in all clear-cell renal cell carcinoma, It may be involved in cell proliferation and transformation, They participate in a variety of biological processes, They show extensive diversity in tissue distribution and in their subcellular localization, This gene was mapped to 17q21, [Wiki], acid-base balance, and gastric acid, and the formation of aqueous humor, bone resorption, but is not detected in normal kidney or most other normal tissues, calcification, cerebrospinal fluid, however, including respiration, radiation hybrid mapping localized it to 9p13-p12, saliva, 2 by fluorescence in situ hybridization, Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide |
| Immunogen: |
A portion of amino acids 63-90 from the human protein was used as the immunogen for this CA9 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CA9 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CA9 (Carbonic Anhydrase IX) |
| Short name: |
CA9 Antibody (Carbonic Anhydrase IX) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CA9 (Antibody to) (Carbonic Anhydrase IX) |
| Alternative technique: |
antibodies |
| Identity: |
1383 |
| Gene: |
CA9 |
More about : CA9 |
| Long gene name: |
carbonic anhydrase 9 |
| Synonyms gene name: |
carbonic anhydrase IX |
| Synonyms: |
MN CAIX |
| Synonyms name: |
carbonic dehydratase RCC-associated protein G250 |
| Locus: |
9p13, 3 |
| Discovery year: |
1998-04-29 |
| GenBank acession: |
X66839 |
| Entrez gene record: |
768 |
| Pubmed identfication: |
8661007 9787087 |
| RefSeq identity: |
NM_001216 |
| Classification: |
Carbonic anhydrases |
| Havana BLAST/BLAT: |
OTTHUMG00000021029 |