| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RUNX2 (phospho-S465) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, DB |
| Recommended dilutions: |
Dot blot: 1:500 |
| Notes: |
Titration of the phospho-RUNX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This phospho-RUNX2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13950 |
| Purity: |
Antigen affinity |
| Description: |
It can bind DNA both as a monomer or, It is a nuclear protein with an Runt DNA-binding domain, Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD), This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression, as a subunit of a heterodimeric complex, with more affinity, Runx2 is a member of the RUNX family of transcription factors |
| Immunogen: |
This phospho-RUNX2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS465 of human RUNX2 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-RUNX2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RUNX2 (phospho-S465) |
| Short name: |
RUNX2 Antibody (phospho-S465) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RUNX2 (Antibody to) (phosphorilated-S465) |
| Alternative technique: |
antibodies |
| Identity: |
10472 |
| Gene: |
RUNX2 |
More about : RUNX2 |
| Long gene name: |
runt related transcription factor 2 |
| Synonyms gene: |
CCD CBFA1 CCD1 |
| Synonyms gene name: |
runt-related transcription factor 2 |
| Synonyms: |
AML3 PEBP2A1 PEBP2aA1 |
| Locus: |
6p21, 1 |
| Discovery year: |
1994-11-02 |
| GenBank acession: |
AF001450 |
| Entrez gene record: |
860 |
| Pubmed identfication: |
7835892 |
| RefSeq identity: |
NM_004348 |
| Havana BLAST/BLAT: |
OTTHUMG00000014774 |