| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Raptor (phospho-S863) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, DB |
| Recommended dilutions: |
Dot blot: 1:500 |
| Notes: |
Titration of the phospho-Raptor antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This phospho-Raptor antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8N122 |
| Purity: |
Antigen affinity |
| Description: |
It has a positive role in nutrient-stimulated signaling to the downstream effector RPS6KB1, It plays a pivotal role as a scaffold protein in the FRAP1-signaling pathway and this interaction is essential for the catalyzed phosphorylation of EIF4EBP1, Regulation of the interaction with FRAP1 is a critical mechanism by which cells coordinate the rate of cell growth and maintenance of cell size with different environmental conditions, Under nutrient-deprived conditions, raptor serves as a negative regulator of FRAP1 kinase activity, Raptor participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1 to form a nutrient-sensitive complex (NSC) |
| Immunogen: |
This phospho-Raptor antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS863 of human Raptor |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-Raptor antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Raptor (phospho-S863) |
| Short name: |
Raptor Antibody (phospho-S863) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Raptor (Antibody to) (phosphorilated-S863) |
| Alternative technique: |
antibodies |