| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Phospho-NFATC2 (pS330) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, DB |
| Recommended dilutions: |
Dot blot: 1:500 |
| Notes: |
Titration of the phospho-NFATC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This phospho-NFATC2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13469 |
| Purity: |
Antigen affinity |
| Description: |
It is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR), This complex plays a central role in inducing gene transcription during the immune response, This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex, NFATC2 is a member of the nuclear factor of activated T cells (NFAT) family |
| Immunogen: |
This phospho-NFATC2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS330 of human NFATC2 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-NFATC2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Phospho-NFATC2 (pS330) |
| Short name: |
Phospho-NFATC2 Antibody (pS330) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
calcineurin-dependent 2 (Antibody to) (pS330), cytoplasmic, phosphorilated-nuclear factor on activated T-cells |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016477 and cell migration and biological process this GO :0030529 and ribonucleoprotein complex and cellular component this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042493 and response to drug and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044798 and nuclear transcription factor complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050853 and B cell receptor signaling pathway and biological process, NFAT1 and NFATP, NFATC2 and IDBG-643253 and ENSBTAG00000018270 and 530401, NFATC2 and IDBG-81223 and ENSG00000101096 and 4773, Nfatc2 and IDBG-213130 and ENSMUSG00000027544 and 18019, calcineurin-dependent 2, cytoplasmic, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001816 and cytokine production and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, transcription regulatory region DNA binding, nuclear factor of activated T-cells |
| Identity: |
7776 |
| Gene: |
NFATC2 |
More about : NFATC2 |
| Long gene name: |
nuclear factor of activated T-cells 2 |
| Synonyms gene name: |
calcineurin-dependent 2 , cytoplasmic, nuclear factor of activated T-cells |
| Synonyms: |
NF-ATP NFATp NFAT1 |
| Locus: |
20q13, 2 |
| Discovery year: |
1994-11-16 |
| GenBank acession: |
U43342 U43341 |
| Entrez gene record: |
4773 |
| Pubmed identfication: |
8202141 |
| RefSeq identity: |
NM_012340 |
| Classification: |
Nuclear factors of activated T-cells |
| Havana BLAST/BLAT: |
OTTHUMG00000032747 |