| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
p-Tuberin (pS939) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IF, DB |
| Recommended dilutions: |
Dot blot: 1:500, Immunofluorescence: 1:10-1:50 |
| Notes: |
Titration of the p-Tuberin antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This p-Tuberin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P49815 |
| Purity: |
Antigen affinity |
| Description: |
Interaction between TSC1 and TSC2 may facilitate vesicular docking, TSC2 may have a function in vesicular transport, The protein associates with hamartin in a cytosolic complex, The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors, possibly acting as a chaperone for hamartin, Mutations in TSC2/Tuberin lead to tuberous sclerosis complex |
| Immunogen: |
This p-Tuberin antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS939 of human TSC2 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the p-Tuberin antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
p-Tuberin (pS939) |
| Short name: |
p-Tuberin Antibody (pS939) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p-Tuberin (Antibody to) (pS939) |
| Alternative technique: |
antibodies |