| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MEF2C (phospho-S396) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, DB |
| Recommended dilutions: |
Dot blot: 1:500 |
| Notes: |
Titration of the phospho-MEF2C antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This phospho-MEF2C antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q06413 |
| Purity: |
Antigen affinity |
| Description: |
It may also be involved in neurogenesis and in the development of cortical architecture, This protein controls cardiac morphogenesis and myogenesis, and is also involved in vascular development, MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes |
| Immunogen: |
This phospho-MEF2C antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS396 of human MEF2C |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-MEF2C antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MEF2C (phospho-S396) |
| Short name: |
MEF2C Antibody (phospho-S396) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
myocyte enhancer factor 2C (Antibody to) (phosphorilated-S396) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C5DELq14, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0006959 and humoral immune response and biological process this GO :0007399 and nervous system development and biological process this GO :0007507 and heart development and biological process this GO :0007517 and muscle organ development and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0007521 and muscle cell fate determination and biological process this GO :0007611 and learning or memory and biological process this GO :0009615 and response to virus and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0010694 and positive regulation of alkaline phosphatase activity and biological process this GO :0014033 and neural crest cell differentiation and biological process this GO :0014898 and cardiac muscle hypertrophy in response to stress and biological process this GO :0014902 and myotube differentiation and biological process this GO :0016607 and nuclear speck and cellular component this GO :0030182 and neuron differentiation and biological process this GO :0030220 and platelet formation and biological process this GO :0030224 and monocyte differentiation and biological process this GO :0030279 and negative regulation of ossification and biological process this GO :0030318 and melanocyte differentiation and biological process this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0033613 and activating transcription factor binding and molecular function this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035198 and miRNA binding and molecular function this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035690 and cellular response to drug and biological process this GO :0035984 and cellular response to trichostatin A and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042100 and B cell proliferation and biological process this GO :0042692 and muscle cell differentiation and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043234 and protein complex and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045652 and regulation of megakaryocyte differentiation and biological process this GO :0045663 and positive regulation of myoblast differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046928 and regulation of neurotransmitter secretion and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048643 and positive regulation of skeletal muscle tissue development and biological process this GO :0048666 and neuron development and biological process this GO :0048667 and cell morphogenesis involved in neuron differentiation and biological process this GO :0048703 and embryonic viscerocranium morphogenesis and biological process this GO :0048704 and embryonic skeletal system morphogenesis and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051963 and regulation of synapse assembly and biological process this GO :0051966 and regulation of synaptic transmission, HMG box domain binding, MEF2C and IDBG-33077 and ENSG00000081189 and 4208, MEF2C and IDBG-646539 and ENSBTAG00000020701 and 512254, Mef2c and IDBG-170220 and ENSMUSG00000005583 and 17260, glutamatergic and biological process this GO :0055007 and cardiac muscle cell differentiation and biological process this GO :0055012 and ventricular cardiac muscle cell differentiation and biological process this GO :0060021 and palate development and biological process this GO :0060025 and regulation of synaptic activity and biological process this GO :0060045 and positive regulation of cardiac muscle cell proliferation and biological process this GO :0060079 and regulation of excitatory postsynaptic membrane potential and biological process this GO :0060297 and regulation of sarcomere organization and biological process this GO :0060536 and cartilage morphogenesis and biological process this GO :0060998 and regulation of dendritic spine development and biological process this GO :0061333 and renal tubule morphogenesis and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071277 and cellular response to calcium ion and biological process this GO :0071374 and cellular response to parathyroid hormone stimulus and biological process this GO :0071498 and cellular response to fluid shear stress and biological process this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process this GO :0071837 and HMG box domain binding and molecular function this GO :0071864 and positive regulation of cell proliferation in bone marrow and biological process this GO :0072102 and glomerulus morphogenesis and biological process this GO :0072160 and nephron tubule epithelial cell differentiation and biological process this GO :0090073 and positive regulation of protein homodimerization activity and biological process this GO :2000111 and positive regulation of macrophage apoptotic process and biological process this GO :2000310 and regulation of N-methyl-D-aspartate selective glutamate receptor activity and biological process this GO :2000311 and regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity and biological process this GO :2000727 and positive regulation of cardiac muscle cell differentiation and biological process this GO :2000987 and positive regulation of behavioral fear response and biological process this GO :2001013 and epithelial cell proliferation involved in renal tubule morphogenesis and biological process this GO :2001016 and positive regulation of skeletal muscle cell differentiation and biological process, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000165 and MAPK cascade and biological process this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0000983 and RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and molecular function this GO :0000987 and core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001046 and core promoter sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001205 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001568 and blood vessel development and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001764 and neuron migration and biological process this GO :0001782 and B cell homeostasis and biological process this GO :0001947 and heart looping and biological process this GO :0001958 and endochondral ossification and biological process this GO :0001974 and blood vessel remodeling and biological process this GO :0002062 and chondrocyte differentiation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002467 and germinal center formation and biological process this GO :0002634 and regulation of germinal center formation and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0002931 and response to ischemia and biological process this GO :0003138 and primary heart field specification and biological process this GO :0003139 and secondary heart field specification and biological process this GO :0003151 and outflow tract morphogenesis and biological process this GO :0003185 and sinoatrial valve morphogenesis and biological process this GO :0003211 and cardiac ventricle formation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003680 and AT DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0000983 : RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and also this GO :0000987 : core promoter proximal region sequence-specific DNA binding and also this GO :0001046 : core promoter sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001205 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003680 : AT DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0033613 : activating transcription factor binding and also this GO :0035198 : miRNA binding and also this GO :0042826 : histone deacetylase binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0046983 : protein dimerization activity and also this GO :0071837 : HMG box domain binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0000983 : RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, this GO :0000987 : core promoter proximal region sequence-specific DNA binding, this GO :0001046 : core promoter sequence-specific DNA binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001205 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003680 : AT DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0033613 : activating transcription factor binding, this GO :0035198 : miRNA binding, this GO :0042826 : histone deacetylase binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046982 : protein heterodimerization activity, this GO :0046983 : protein dimerization activity, this GO :0071837 : HMG box domain binding, 3, 3 and DEL5q14, myocyte enhancer factor 2C |
| Identity: |
6996 |
| Gene: |
MEF2C |
More about : MEF2C |
| Long gene name: |
myocyte enhancer factor 2C |
| Locus: |
5q14, 3 |
| Discovery year: |
1995-02-08 |
| GenBank acession: |
AL833268 |
| Entrez gene record: |
4208 |
| Pubmed identfication: |
8455629 |
| RefSeq identity: |
NM_002397 |
| Classification: |
Myocyte enhancer factor 2 proteins MADS box family |
| Havana BLAST/BLAT: |
OTTHUMG00000162634 |