p70S6K Antibody

Catalog number:	F48468-0.4ML Buy Now
Price:	602 €
Supplier:	genways
Product name:	p70S6K Antibody
Quantity:	1 x 1 vial
Other quantities:	100ug 647€
Related search:	antibody psk complex antibodies cell deg alternative concentration

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Category:	Antibody
Concentration:	pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form:	Antigen affinity purified
Conjugation:	Unconjugated
Clone:	Polyclonal antibody
Recognised antigen:	p70S6K
Host animal:	Rabbit (Oryctolagus cuniculus)
Clonality:	Polyclonal (rabbit origin)
Species reactivity:	Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications:	ELISA, IHC, WB
Recommended dilutions:	IHC (Paraffin): 1:10-1:50, Western blot: 1:1000
Notes:	Titration of the p70S6K antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented use:	This p70S6K antibodyis to be used only for research purposes and not for diagnostics
Uniprot #:	P23443
Purity:	Antigen affinity
Description:	RPS6 and EEF2K, Regulates protein synthesis through phosphorylation of EIF4B, The active form then phosphorylates and activates several substrates in the pre-initiation complex, Under conditions of nutrient depletion, Upon mitogenic stimulation, [UniProt], and contributes to cell survival by repressing the pro-apoptotic function of BAD, cell growth and cell cycle progression, including the EIF2B complex and the cap-binding complex component EIF4B, phosphorylation by the mammalian target of rapamycin complex 1 (mTORC1) leads to dissociation from the EIF3 complex and activation, the inactive form associates with the EIF3 translation initiation complex, RPS6kB1 is a serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation
Immunogen:	A portion of amino acids 425-454 from human RPS6KB1 was used as the immunogen for this p70S6K antibody
Storage:	Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the p70S6K antibody and store frozen at -20 deg
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target:	p70S6K
Short name:	p70S6K Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	p70S6K (Antibody to)
Alternative technique:	antibodies

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