| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Phospho-TNFR (pS274) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the phospho-TNFR antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This phospho-TNFR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P19438 |
| Purity: |
Antigen affinity |
| Description: |
Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome, The impaired receptor clearance is thought to be a mechanism of the disease, This receptor can activate NF-kappaB, and function as a regulator of inflammation, and thus play regulatory roles in the signal transduction mediated by the receptor, mediate apoptosis, this protein is one of the major receptors for the tumor necrosis factor-alpha, A member of the TNF-receptor superfamily |
| Immunogen: |
This phospho-TNFR antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS274 of human TNFR |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-TNFR antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Phospho-TNFR (pS274) |
| Short name: |
Phospho-TNFR Antibody (pS274) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
phosphorilated-TNFR (Antibody to) (pS274) |
| Alternative technique: |
antibodies |