| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Phospho-KDR (pY996) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the phospho-KDR antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This phospho-KDR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P35968 |
| Purity: |
Antigen affinity |
| Description: |
The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability, This protein has a tyrosine-protein kinase activity, KDR (FLK1) is a receptor for VEGF or VEGFC |
| Immunogen: |
This phospho-KDR antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY996 of human KDR/FLK1 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-KDR antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Phospho-KDR (pY996) |
| Short name: |
Phospho-KDR Antibody (pY996) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
phosphorilated-kinase insert domain receptor (a type III receptor tyrosine kinase) (Antibody to) (pY996) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD309 and FLK1 and VEGFR and VEGFR2, KDR and IDBG-19161 and ENSG00000128052 and 3791, KDR and IDBG-642352 and ENSBTAG00000000782 and 407170, Kdr and IDBG-172240 and ENSMUSG00000062960 and 16542, nuclei, this GO :0001525 and angiogenesis and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0001945 and lymph vessel development and biological process this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003158 and endothelium development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0005021 and vascular endothelial growth factor-activated receptor activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016032 and viral process and biological process this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004716 : receptor signaling protein tyrosine kinase activity and also this GO :0005021 : vascular endothelial growth factor-activated receptor activity and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004716 : receptor signaling protein tyrosine kinase activity, this GO :0005021 : vascular endothelial growth factor-activated receptor activity, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019838 : growth factor binding, this GO :0038085 : vascular endothelial growth factor binding, this GO :0051879 : Hsp90 protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019838 : growth factor binding and also this GO :0038085 : vascular endothelial growth factor binding and also this GO :0051879 : Hsp90 protein binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030054 and cell junction and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030324 and lung development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0035162 and embryonic hemopoiesis and biological process this GO :0035584 and calcium-mediated signaling using intracellular calcium source and biological process this GO :0035924 and cellular response to vascular endothelial growth factor stimulus and biological process this GO :0038083 and peptidyl-tyrosine autophosphorylation and biological process this GO :0038084 and vascular endothelial growth factor signaling pathway and biological process this GO :0038085 and vascular endothelial growth factor binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043129 and surfactant homeostasis and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045121 and membrane raft and cellular component this GO :0045165 and cell fate commitment and biological process this GO :0045446 and endothelial cell differentiation and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048010 and vascular endothelial growth factor receptor signaling pathway and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048469 and cell maturation and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050927 and positive regulation of positive chemotaxis and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0051879 and Hsp90 protein binding and molecular function this GO :0051894 and positive regulation of focal adhesion assembly and biological process this GO :0055074 and calcium ion homeostasis and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071944 and cell periphery and cellular component this GO :0097443 and sorting endosome and cellular component this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process this GO :2001214 and positive regulation of vasculogenesis and biological process, kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Identity: |
6307 |
| Gene: |
KDR |
More about : KDR |
| Long gene name: |
kinase insert domain receptor |
| Synonyms gene name: |
kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Synonyms: |
FLK1 VEGFR VEGFR2 CD309 |
| Synonyms name: |
vascular endothelial growth factor receptor 2 fetal liver kinase 1 |
| Locus: |
4q12 |
| Discovery year: |
1991-07-10 |
| GenBank acession: |
AF035121 |
| Entrez gene record: |
3791 |
| Pubmed identfication: |
1417831 |
| Classification: |
I-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000128734 |
| Locus Specific Databases: |
The Globin Gene Server |