| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PAX3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, WB, IHC |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the PAX3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PAX3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P23760 |
| Purity: |
Antigen affinity |
| Description: |
PAX3 probable is a transcription factor associated with development of alveolar rhabdomyosarcoma |
| Immunogen: |
A portion of amino acids 98-126 from the human protein was used as the immunogen for this PAX3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PAX3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PAX3 |
| Short name: |
PAX3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
paired box 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CDHS and HUP2 and WS1 and WS3, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007507 and heart development and biological process this GO :0007517 and muscle organ development and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0014807 and regulation of somitogenesis and biological process this GO :0016477 and cell migration and biological process this GO :0021527 and spinal cord association neuron differentiation and biological process this GO :0021915 and neural tube development and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048066 and developmental pigmentation and biological process this GO :0048663 and neuron fate commitment and biological process this GO :0060594 and mammary gland specification and biological process this GO :0071837 and HMG box domain binding and molecular function, HMG box domain binding, PAX3 and IDBG-82144 and ENSG00000135903 and 5077, Pax3 and IDBG-172194 and ENSMUSG00000004872 and 18505, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0001843 and neural tube closure and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0071837 : HMG box domain binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, this GO :0071837 : HMG box domain binding, 97999 and IDBG-644149 and ENSBTAG00000009950 and 540951, paired box 3 |
| Identity: |
8617 |
| Gene: |
PAX3 |
More about : PAX3 |
| Long gene name: |
paired box 3 |
| Synonyms gene: |
WS1 |
| Synonyms gene name: |
Waardenburg syndrome 1 paired box gene 3 (Waardenburg syndrome 1) |
| Synonyms: |
HUP2 |
| Locus: |
2q36, 1 |
| Discovery year: |
1992-01-14 |
| Entrez gene record: |
5077 |
| Pubmed identfication: |
1347149 |
| Classification: |
PRD class homeoboxes and pseudogenes Paired boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000133157 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database |