| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
EZH1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IHC |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the EZH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This EZH1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q92800 |
| Purity: |
Purified |
| Description: |
Analysis of an EZH1 cDNA revealed an unusual splicing event involving EZH1 and a tandemly linked gene GPR2 and suggested a potential mechanism for modifying the EZH1 protein in the conserved C-terminal domain, EZH1 is expressed as 2 major transcripts in all adult and fetal human tissues evaluated, The GPR2 gene maps to 17q21, 1 The strong sequence conservation suggested potential roles for EZH1 in human development as a transcriptional regulator and as a component of protein complexes that preserve heterochromatin stability, 1-q21, 3 in the vicinity of the BRCA1 gene, EZH1 encodes a protein of 747 amino acids that displays 55% amino acid identity overall with the Drosophila homolog |
| Immunogen: |
A portion of amino acids 393-422 from the human protein was used as the immunogen for this EZH1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the EZH1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
EZH1 |
| Short name: |
EZH1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
EZH1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3526 |
| Gene: |
EZH1 |
More about : EZH1 |
| Long gene name: |
enhancer of zeste 1 polycomb repressive complex 2 subunit |
| Synonyms gene name: |
enhancer of zeste (Drosophila) homolog 1 enhancer of zeste homolog 1 (Drosophila) |
| Synonyms: |
KIAA0388 KMT6B |
| Locus: |
17q21, 2 |
| Discovery year: |
1995-12-21 |
| Entrez gene record: |
2145 |
| Pubmed identfication: |
8921387 |
| RefSeq identity: |
NM_001991 |
| Classification: |
Polycomb repressive complex 2 Lysine methyltransferases Myb/SANT domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180645 |