| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
GDF11 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the GDF11 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This GDF11 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O95390 |
| Purity: |
Purified |
| Description: |
Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development, The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues, This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues, GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily |
| Immunogen: |
A portion of amino acids 32-61 from the human protein was used as the immunogen for this GDF11 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the GDF11 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
GDF11 |
| Short name: |
GDF11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
growth differentiation factor 11 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BMP-11 and BMP11, Extracellular, GDF11 and IDBG-39057 and ENSG00000135414 and 10220, GDF11 and IDBG-636472 and ENSBTAG00000007417 and 540517, Gdf11 and IDBG-198554 and ENSMUSG00000025352 and 14561, growth factor activity, this GO :0001501 and skeletal system development and biological process this GO :0001656 and metanephros development and biological process this GO :0001657 and ureteric bud development and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005575 and cellular component and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007399 and nervous system development and biological process this GO :0007498 and mesoderm development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0021512 and spinal cord anterior/posterior patterning and biological process this GO :0031016 and pancreas development and biological process this GO :0040007 and growth and biological process this GO :0043234 and protein complex and cellular component this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0048469 and cell maturation and biological process this GO :0048593 and camera-type eye morphogenesis and biological process this GO :0060021 and palate development and biological process, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, growth differentiation factor 11 |
| Identity: |
4216 |
| Gene: |
GDF11 |
More about : GDF11 |
| Long gene name: |
growth differentiation factor 11 |
| Synonyms: |
BMP-11 |
| Locus: |
12q13, 2 |
| Discovery year: |
1999-12-02 |
| GenBank acession: |
AF100907 |
| Entrez gene record: |
10220 |
| Pubmed identfication: |
15988002 |
| Havana BLAST/BLAT: |
OTTHUMG00000170188 |