SLUG Antibody

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Catalog number: F47912-0.4ML
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: SLUG Antibody
Quantity: 0.1ml
Other quantities: 0.1ml 263€ 1 tube 532€ 100ug 431€ 50ug 365€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: SLUG
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, WB
Recommended dilutions: Western blot: 1:1000
Notes: Titration of the SLUG antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This SLUG antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: O43623
Purity: Purified
Description: Binds to CXCL12 promoter via E-box regions in mesenchymal stem cells and osteoblasts, Binds to E-box2 domain of BSG and activates its expression during TGFB1-induced epithelial-mesenchymal transition (EMT) in hepatocytes, Binds to RUNX2 and SOC9 promoters and may act as a positive and negative transcription regulator, In epidermal keratinocytes, Involved in osteoblast maturation, Involved in the generation and migration of neural crest cells, Involved in the regulation of&, Plays a role in mediating RAF1-induced transcriptional repression of the TJ protein, Plays an essential role in TWIST1-induced EMT and its ability to promote invasion and metastasis, Represses BRCA2 expression by binding to its E2-box-containing silencer and recruiting&, Represses&, [UniProt], binds to the E-box in&, in osteoblasts, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity), respectively, &, &, &, &, &, <, <, <, <, <, <, /CDH1 transcription via E-box elements, /a>, /a>, /a>, /a>, /a>, /a>, /search_result, /search_result, /search_result, /search_result, /search_result, /search_result, CTBP1<, E-Cadherin<, HDAC1<, ITGA3<, ITGB1<, ITGB4<, SNAI2/SLUG is a transcriptional repressor that modulates both activator-dependent and basal transcription, a href=, a href=, a href=, a href=, a href=, a href=, and&, and&, expression and cell adhesion and proliferation in epidermal keratinocytes, in breast cells, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, php?search_txt=ctbp>, php?search_txt=e-cadherin>, php?search_txt=hdac1>, php?search_txt=itga3>, php?search_txt=itgb1>, php?search_txt=itgb4>, promoter and represses its transcription
Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this SLUG antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SLUG antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: SLUG
Short name: SLUG Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: SLUG (Antibody to)
Alternative technique: antibodies
Identity: 11094
Gene: SNAI2 | More about : SNAI2
Long gene name: snail family transcriptional repressor 2
Synonyms gene: SLUG
Synonyms gene name: slug homolog, zinc finger protein (chicken) snail homolog 2 (Drosophila) snail family zinc finger 2
Synonyms: SLUGH1 SNAIL2 SLUGH
Locus: 8q11, 21
Discovery year: 1998-07-03
GenBank acession: U97060
Entrez gene record: 6591
Pubmed identfication: 9337409 9721220
RefSeq identity: NM_003068
Classification: Zinc fingers C2H2-type SNAG transcriptional repressors
Havana BLAST/BLAT: OTTHUMG00000149912

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