| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ALK3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IHC |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the ALK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ALK3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P36894 |
| Purity: |
Purified |
| Description: |
ACVR1 and ACVR2, TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD, The ligands of these receptors are members of the TGF-beta superfamily, These receptors are also closely related to the activin receptors, Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding, The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A/ALK3 and BMPR1B and the type II receptor BMPR2 |
| Immunogen: |
A portion of amino acids 30-60 from the human protein was used as the immunogen for this ALK3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ALK3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ALK3 |
| Short name: |
ALK3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ALK3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1076 |
| Gene: |
BMPR1A |
More about : BMPR1A |
| Long gene name: |
bone morphogenetic protein receptor type 1A |
| Synonyms gene: |
ACVRLK3 |
| Synonyms gene name: |
bone morphogenetic protein receptor, type IA |
| Synonyms: |
ALK3 CD292 |
| Locus: |
10q23, 2 |
| Discovery year: |
1994-12-12 |
| GenBank acession: |
BC028383 |
| Entrez gene record: |
657 |
| Pubmed identfication: |
8397373 9730621 |
| RefSeq identity: |
NM_004329 |
| Classification: |
Type 1 receptor serine/threonine kinases CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000018657 |
| Locus Specific Databases: |
LRG_298 |