| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NEU1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the NEU1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This NEU1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q99519 |
| Purity: |
Antigen affinity |
| Description: |
In the lysosome, Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), or type 2 (the dysmorphic type), this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'), which is late-onset, which occurs at an earlier age with increased severity, The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids |
| Immunogen: |
A portion of amino acids 188-214 from the human protein was used as the immunogen for this NEU1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NEU1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NEU1 |
| Short name: |
NEU1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NEU1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7758 |
| Gene: |
NEU1 |
More about : NEU1 |
| Long gene name: |
neuraminidase 1 |
| Synonyms gene: |
NEU |
| Synonyms gene name: |
sialidase 1 (lysosomal sialidase) neuraminidase 1 (lysosomal sialidase) |
| Locus: |
6p21, 33 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
AF040958 |
| Entrez gene record: |
4758 |
| Pubmed identfication: |
9054950 |
| Havana BLAST/BLAT: |
OTTHUMG00000031284 |