| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Activator protein 2), AP2 alpha (TFAP2A |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the AP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This AP2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P05549 |
| Purity: |
Antigen affinity |
| Description: |
AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle, AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, C/EBP alpha and MYC, They also suppress a number of genes including MCAM/MUC18, body wall, face, limbs and neural tube development, Activator protein 2 is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes |
| Immunogen: |
A portion of amino acids 104-133 from the human protein was used as the immunogen for this AP2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AP2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Activator protein 2), AP2 alpha (TFAP2A |
| Short name: |
Activator protein 2), AP2 alpha Antibody (TFAP2A |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Activator protein 2), AP2 a (Antibody to) (TFAP2A |
| Alternative technique: |
antibodies |
| Identity: |
11742 |
| Gene: |
TFAP2A |
More about : TFAP2A |
| Long gene name: |
transcription factor AP-2 alpha |
| Synonyms gene: |
TFAP2 AP2TF |
| Synonyms gene name: |
transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha) transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| Synonyms: |
AP-2 |
| Locus: |
6p24, 3 |
| Discovery year: |
1991-09-12 |
| GenBank acession: |
X52611 |
| Entrez gene record: |
7020 |
| Pubmed identfication: |
1916817 3063603 |
| RefSeq identity: |
NM_003220 |
| Havana BLAST/BLAT: |
OTTHUMG00000014235 |