| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Complement C8 beta (C8B) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the C8B antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This C8B antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P07358 |
| Purity: |
Antigen affinity |
| Description: |
C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells, Patients with C8B deficiency are prone to bacteria infection, C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system |
| Immunogen: |
A portion of amino acids 393-422 from the human protein was used as the immunogen for this C8B antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the C8B antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Complement C8 beta (C8B) |
| Short name: |
Complement C8 beta Antibody (C8B) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
beta polypeptide), Complement C8 b (Antibody to) (complement component 8 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, C82, C8B and IDBG-99157 and ENSG00000021852 and 732, C8b and IDBG-169581 and ENSMUSG00000029656 and 110382, Extracellular, alternative pathway and biological process this GO :0006958 and complement activation, beta polypeptide, classical pathway and biological process this GO :0016020 and membrane and cellular component this GO :0019835 and cytolysis and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0032403 and protein complex binding and molecular function this GO :0045087 and innate immune response and biological process, protein complex binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005579 and membrane attack complex and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006955 and immune response and biological process this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0032403 : protein complex binding, this GO :0032403 : protein complex binding, 19507 and IDBG-638889 and ENSBTAG00000003775 and 513217, complement component 8 |
| Identity: |
1353 |
| Gene: |
C8B |
More about : C8B |
| Long gene name: |
complement C8 beta chain |
| Synonyms gene name: |
beta polypeptide , complement component 8 |
| Locus: |
1p32, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M16973 |
| Entrez gene record: |
732 |
| Classification: |
Complement system |
| Havana BLAST/BLAT: |
OTTHUMG00000008305 |
| Locus Specific Databases: |
C8Bbase: Mutation registry for C8B deficiency LRG_31 |