| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PTBP1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the PTBP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PTBP1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P26599 |
| Purity: |
Antigen affinity |
| Description: |
Alternatively spliced transcript variants encoding different isoforms have been described, It may also promote the binding of U2 snRNP to pre-mRNAs, The hnRNP proteins have distinct nucleic acid binding properties, The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA), The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs, These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport, This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway, This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure, While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm, This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) |
| Immunogen: |
A portion of amino acids 26-55 from the human protein was used as the immunogen for this PTBP1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PTBP1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PTBP1 |
| Short name: |
PTBP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PTBP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9583 |
| Gene: |
PTBP1 |
More about : PTBP1 |
| Long gene name: |
polypyrimidine tract binding protein 1 |
| Synonyms gene: |
PTB |
| Synonyms gene name: |
polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) |
| Synonyms: |
HNRPI HNRNP-I PTB2 PTB3 PTB-1 PTB4 pPTB |
| Synonyms name: |
heterogeneous nuclear ribonucleoprotein I |
| Locus: |
19p13, 3 |
| Discovery year: |
1992-06-29 |
| GenBank acession: |
X60648 |
| Entrez gene record: |
5725 |
| Pubmed identfication: |
1906036 11024286 |
| RefSeq identity: |
NM_002819 |
| Classification: |
RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000181789 |