| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TBR2 (EOMES) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the TBR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This TBR2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O95936 |
| Purity: |
Antigen affinity |
| Description: |
A similiar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation, T-box genes encode transcription factors involved in the regulation of developmental processes, also called EOMES, is a member of a conserved protein family that shares a common DNA-binding domain, the T-box, T-box Brain protein 2 |
| Immunogen: |
A portion of amino acids 28-57 from the human protein was used as the immunogen for this EOMES / TBR2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TBR2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TBR2 (EOMES) |
| Short name: |
TBR2 Antibody (EOMES) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TBR2 (Antibody to) (eomesodermin) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007420 and brain development and biological process this GO :0010002 and cardioblast differentiation and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0021772 and olfactory bulb development and biological process this GO :0021796 and cerebral cortex regionalization and biological process this GO :0021895 and cerebral cortex neuron differentiation and biological process this GO :0030154 and cell differentiation and biological process this GO :0032609 and interferon-gamma production and biological process this GO :0035914 and skeletal muscle cell differentiation and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045664 and regulation of neuron differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050767 and regulation of neurogenesis and biological process this GO :0060706 and cell differentiation involved in embryonic placenta development and biological process this GO :0060809 and mesodermal to mesenchymal transition involved in gastrulation and biological process, EOMES and IDBG-23119 and ENSG00000163508 and 8320, EOMES and IDBG-644058 and ENSBTAG00000016920 and 511947, Eomes and IDBG-204135 and ENSMUSG00000032446 and 13813, TBR2, alpha-beta T cell differentiation involved in immune response and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0001102 and RNA polymerase II activating transcription factor binding and molecular function this GO :0001191 and RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001706 and endoderm formation and biological process this GO :0001707 and mesoderm formation and biological process this GO :0001714 and endodermal cell fate specification and biological process this GO :0001824 and blastocyst development and biological process this GO :0001829 and trophectodermal cell differentiation and biological process this GO :0002302 and CD8-positive, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0001102 : RNA polymerase II activating transcription factor binding and also this GO :0001191 : RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0043565 : sequence-specific DNA binding, this GO :0001102 : RNA polymerase II activating transcription factor binding, this GO :0001191 : RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0043565 : sequence-specific DNA binding, eomesodermin |
| Identity: |
3372 |
| Gene: |
EOMES |
More about : EOMES |
| Long gene name: |
eomesodermin |
| Synonyms gene name: |
eomesodermin (Xenopus laevis) homolog |
| Synonyms: |
TBR2 |
| Synonyms name: |
T-box brain2 |
| Locus: |
3p24, 1 |
| Discovery year: |
1998-09-15 |
| GenBank acession: |
BC025363 |
| Entrez gene record: |
8320 |
| Pubmed identfication: |
9888994 9434949 |
| RefSeq identity: |
NM_005442 |
| Classification: |
T-boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000130570 |